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Proposal of topology of piezoceramic composite sensor
Dostal, Vojtěch ; Ševeček, Oldřich (referee) ; Majer, Zdeněk (advisor)
This master thesis deals with design and numerical modelling of piezoceramic sensor, which is placed on a rail, in order to generate electrical energy, which can be used for wireless monitoring of railway traffic and to monitor the condition of the railway. The thesis is divided into three parts. Theoretically background of piezoelectric energy harvesting is described in first part, where some previous application of piezoelectric generator in railway area are shown. In the second part, parametric analysis of numerical model is performed, which directly leads to finding best location on a rail, where piezoelectric generator should be placed. For this analysis the homogenized model of MFC sensor was used. Results of the numerical model were then compared with the results of the conducted experiment. The third part presented own design of piezoceramic sensor, which is placed onto most suitable location on a rail. Results from numerical analysis shown eligibility of using piezoceramic sensor to monitor the railway traffic.
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Description Methods for Electrical Systems and Their Solving
Křižka, Jakub ; Němec, Zdeněk (referee) ; Šeda, Miloš (advisor)
The objective of bachelor thesis is a searching description of methods, which are usually used for calculation of circuit variable values in electric circuits. At the beginning is thesis concerning with description of individual components (power supplies, electronic components) used in electric circuits, then also with analysis of rules, which are the fundamental for a calculation of values in electronic circuit – Ohm’s rule and Kirchhoff’s rules. Indivisible part of thesis is also summary of special methods, such as method of loop currents (mesh analysis), method of nodal voltage (nodal analysis) etc. and their demonstration on examples of electric circuits. The structure of thesis is coursebook and gives successive summary of information in area calculations of electric circuits.
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Proposal of topology of piezoceramic composite sensor
Dostal, Vojtěch ; Ševeček, Oldřich (referee) ; Majer, Zdeněk (advisor)
This master thesis deals with design and numerical modelling of piezoceramic sensor, which is placed on a rail, in order to generate electrical energy, which can be used for wireless monitoring of railway traffic and to monitor the condition of the railway. The thesis is divided into three parts. Theoretically background of piezoelectric energy harvesting is described in first part, where some previous application of piezoelectric generator in railway area are shown. In the second part, parametric analysis of numerical model is performed, which directly leads to finding best location on a rail, where piezoelectric generator should be placed. For this analysis the homogenized model of MFC sensor was used. Results of the numerical model were then compared with the results of the conducted experiment. The third part presented own design of piezoceramic sensor, which is placed onto most suitable location on a rail. Results from numerical analysis shown eligibility of using piezoceramic sensor to monitor the railway traffic.
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Effect of calcium ions and cholesterol on channel forming activity of Adenylate-cyclase toxin
Doktorová, Eliška ; Fišer, Radovan (advisor) ; Horák, Martin (referee)
1 Abstract Adenylate cyclase toxin (CyaA) is one of the major virulence factors of bacterium Bordetella pertussis, which is a causative agent of whooping cough. CyaA belongs to the family of RTX toxin-hemolysins. The toxin targets primarily cells expressing integrin receptor CD11b/CD18 but it can also penetrate cells lacking this receptor. CyaA acts on host cells by two independent activities. One is formation of small cation-selective channels, which can lead to colloid osmotic lysis of target cells. The second is disruption of cell signaling through the translocation of the adenylate cyclase (AC) domain to host cell cytosol, which leads to the conversion of ATP into cyclic AMP. It was recently shown that cholesterol affects endocytosis of CyaA. CyaA translocates it's AC domain after relocation of CyaA molecule to the cholesterol-rich lipid raft (Bumba et al. 2010). In this work I examined the effect of cholesterol on channel- forming activity and selectivity of ion channels created by CyaA. For measurements I used artificial membranes enriched with cholesterol. CyaA channels are voltage-dependent. The positive membrane potential on the side of toxin is rquired for incorporation of CyaA molecule into cell membrane. I tried to find out whether the value of voltage has effect on channels opening time....
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Description Methods for Electrical Systems and Their Solving
Křižka, Jakub ; Němec, Zdeněk (referee) ; Šeda, Miloš (advisor)
The objective of bachelor thesis is a searching description of methods, which are usually used for calculation of circuit variable values in electric circuits. At the beginning is thesis concerning with description of individual components (power supplies, electronic components) used in electric circuits, then also with analysis of rules, which are the fundamental for a calculation of values in electronic circuit – Ohm’s rule and Kirchhoff’s rules. Indivisible part of thesis is also summary of special methods, such as method of loop currents (mesh analysis), method of nodal voltage (nodal analysis) etc. and their demonstration on examples of electric circuits. The structure of thesis is coursebook and gives successive summary of information in area calculations of electric circuits.
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